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Pharmaceutical agents and pregnancy in urology practice
Alon Shrim1, Facundo Garcia-Bournissen, Gideon Koren
1The Motherisk Program, Division of Clinical Pharmacology/Toxicology, Hospital for Sick Children, The University of Toronto, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8.
The Urologic Clinics of North America
|December 6, 2006
Summary
Urologists may prescribe nitrofurantoin for simple urinary tract infections and fluoroquinolones for complex infections in pregnant women. This review covers implications of these common urologic conditions and nonobstetric surgery during pregnancy.
Area of Science:
- Urology
- Obstetrics
- Pharmacology
Background:
- Urologic conditions are uncommon in pregnancy but may require pharmacologic intervention.
- Prescriptions are typically for infections or surgical procedures in healthy pregnant women.
Purpose of the Study:
- To review the implications of common urologic conditions during pregnancy.
- To discuss the use of nitrofurantoin and fluoroquinolones in pregnant patients.
- To examine the impact of nonobstetric surgical interventions in pregnancy.
Main Methods:
- Literature review of urologic conditions in pregnancy.
- Analysis of pharmacologic treatments for urinary tract infections (UTIs) in pregnant women.
- Discussion of surgical management considerations.
Main Results:
- Simple UTIs in pregnancy often treated with nitrofurantoin.
- Complex UTIs in pregnancy may necessitate fluoroquinolones.
- Nonobstetric surgical procedures require careful consideration of maternal and fetal health.
Conclusions:
- Management of urologic conditions in pregnancy requires careful consideration of medication safety and surgical risks.
- Nitrofurantoin and fluoroquinolones are options for UTIs, with specific indications.
- Interdisciplinary collaboration is crucial for optimal outcomes.
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