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Pregnancy and interstitial cystitis/painful bladder syndrome
Deborah R Erickson1, Kathleen J Propert
1Division of Urology, Department of Surgery, University of Kentucky College of Medicine, University of Kentucky Chandler Medical Center, 800 Rose Street, Room MS-269, Lexington, KY 40536, USA. dreric2@email.uky.edu
The Urologic Clinics of North America
|December 6, 2006
Summary
Painful bladder syndrome (PBS) and interstitial cystitis (IC) can impact women of childbearing age. This review covers pregnancy effects on PBS/IC, treatment risks during pregnancy, and genetic factors in IC.
Area of Science:
- Urology
- Gynecology
- Reproductive Medicine
Background:
- Painful bladder syndrome (PBS) and interstitial cystitis (IC) are chronic conditions affecting women, often during reproductive years.
- Management of PBS/IC during pregnancy presents unique challenges due to potential treatment risks and symptom variability.
Purpose of the Study:
- To provide an overview of current knowledge regarding pregnancy in women with PBS/IC.
- To discuss the impact of pregnancy on PBS/IC symptoms.
- To review the safety and risks of common PBS/IC treatments during pregnancy.
- To summarize current understanding of genetic factors in IC.
Main Methods:
- Literature review of studies on pregnancy, PBS/IC, and related treatments.
- Synthesis of available data on symptom changes during pregnancy.
- Analysis of risks associated with pharmaceutical and non-pharmaceutical interventions.
- Review of research on the genetic basis of IC.
Main Results:
- Limited data exists on how pregnancy influences PBS/IC symptoms.
- Several common PBS/IC treatments carry potential risks during pregnancy, requiring careful consideration.
- Emerging research is exploring the genetic underpinnings of interstitial cystitis.
Conclusions:
- Pregnant women with PBS/IC and their clinicians need information on symptom management and treatment safety.
- Further research is necessary to understand pregnancy's effect on PBS/IC and to identify safer treatment options.
- Genetic research may offer future insights into IC etiology and personalized treatment approaches.
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