Related Experiment Videos
Ab initio investigations on the intermediates of RNA cleaving processes
T Uchimaru1, K Tanabe, M Ucbayasi
1National Chemical Laboratory for Industry, Agency of Industrial Science & Technology, MITI, Tsukuba Science City, Japan.
Nucleic Acids Symposium Series
|January 1, 1990
Abstract:
Ab initio molecular orbital calculations have been carried out on acyclic oxyphosphoranes in order to elucidate the origin of previously calculated energy differences of cyclic counterparts of RNA cleaving reactions. It appears that the orientation of the equatorial methoxyl group has pronounced effects in energy on the transition states than the metastable intermediates.