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Pseudallescheria boydii keratitis.

Jay C Bradley1, Benjamin A Hirsch, Robert C Kimbrough

  • 1Department of Ophthalmology & Visual Sciences, Texas Tech University Health Sciences Center, Lubbock, Texas, USA. jay.bradley@aol.com

Scandinavian Journal of Infectious Diseases
|December 7, 2006
PubMed
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A rare fungal eye infection, Pseudallescheria boydii keratitis, was successfully treated. The combination of antifungal medications and corneal transplant restored the patient's vision.

Area of Science:

  • Ophthalmology
  • Mycology

Background:

  • Fungal keratitis poses a significant threat to vision, particularly in cases caused by rare or resistant organisms.
  • Pseudallescheria boydii is an opportunistic fungus that can cause severe ocular infections.

Observation:

  • A patient presented with severe keratitis attributed to Pseudallescheria boydii.

Findings:

  • Successful treatment involved a multi-modal approach: topical natamycin, systemic itraconazole, and penetrating keratoplasty.
  • The patient achieved a final visual acuity of 20/40 post-treatment.

Implications:

  • This case highlights the efficacy of combined antifungal therapy and surgical intervention for Pseudallescheria boydii keratitis.
  • It underscores the importance of prompt diagnosis and aggressive management for sight-threatening fungal eye infections.

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