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[Retroperitoneal inflammatory fibrosarcoma; a case report].
Masayuki Kobayashi1, Satoko Kojima, Takahito Suyama
1Department of Urology, Graduate School of Medicine, Chiba University.
Nihon Hinyokika Gakkai Zasshi. the Japanese Journal of Urology
|December 13, 2006
Summary
A case study highlights inflammatory fibrosarcoma, a rare tumor. Chemotherapy with vincristine, actinomycin-D, and cyclophosphamide (VAC) showed effectiveness in reducing tumor size, offering a potential treatment for inoperable cases.
Area of Science:
- Oncology
- Medical Imaging
- Surgical Pathology
Background:
- Inflammatory fibrosarcoma is a rare soft tissue tumor with variable presentation.
- Pelvic tumors can present with abdominal mass and unintentional weight loss.
- Advanced imaging like CT and MRI are crucial for tumor characterization and staging.
Observation:
- A 62-year-old male presented with a lower abdominal mass and significant weight loss.
- Imaging revealed a large pelvic tumor invading the inferior vena cava up to the renal pedicle.
- Histopathological diagnosis confirmed inflammatory fibrosarcoma.
Findings:
- The patient received five cycles of chemotherapy using vincristine, actinomycin-D, and cyclophosphamide (VAC).
- This regimen resulted in a 35% reduction in tumor volume in one dimension.
- VAC chemotherapy demonstrated efficacy in managing this inoperable inflammatory fibrosarcoma.
Implications:
- Chemotherapy with VAC offers a potential therapeutic option for patients with inoperable inflammatory fibrosarcoma.
- This case underscores the importance of multidisciplinary approaches in managing rare tumors.
- Further research is warranted to establish optimal treatment protocols for inflammatory fibrosarcoma.