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Development of reformative surgery method using partial freezing for the liver.

M Takahashi¹, S Nomura, M Jindai

¹takahashi@eng.ehime-u.ac.jp

Journal of Biomechanical Engineering

|December 13, 2006

Summary

This study explored partial liver freezing to reduce surgical stress during hepatic resection. Optimal freezing temperatures between 272 K and 275 K minimize excision force, aiding safer liver surgery.

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Area of Science:

Surgical Innovation
Biomedical Engineering
Materials Science

Background:

Hepatic resection can involve significant surgical stress, including blood loss and prolonged operation times.
Minimizing these stresses is crucial for patient outcomes in liver surgery.

Purpose of the Study:

To investigate the feasibility of a novel partial liver freezing technique combined with shape-memory alloy for hepatic resection.
To determine the optimal freezing parameters for reducing excision force during liver surgery.

Main Methods:

A Peltier module was used to freeze porcine liver samples.
Excision force was measured using a robotic scalpel system.
Finite element analysis was employed to estimate liver physical properties based on heat transfer.

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Main Results:

The minimum liver excision force was achieved at temperatures between 272 K and 275 K.
A lower cooling rate significantly decreased excision force, independent of temperature.
Higher cooling rates led to a greater increase in excision force at lower temperatures.

Conclusions:

Partial liver freezing within the 272 K to 275 K range is a promising method to reduce excision force during hepatic resection.
Controlling cooling rates is essential for optimizing the effectiveness of this surgical technique.
This approach has the potential to minimize surgical stress, blood loss, and operation time in liver surgery.