Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 18, 2026

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
08:22

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

Recent developments in optical coherence tomography for imaging the retina.

Mirjam E J van Velthoven1, Dirk J Faber, Frank D Verbraak

  • 1Department of Ophthalmology, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands. m.e.vanvelthoven@amc.uva.nl

Progress in Retinal and Eye Research
|December 13, 2006
PubMed
Summary

Optical coherence tomography (OCT) has revolutionized retinal diagnostics. Recent advancements in spectral-domain OCT and functional OCT offer enhanced imaging speed, resolution, and new diagnostic capabilities for eye diseases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evidence and Consensus Based Guidelines for Imaging in Tubercular Choroiditis. Multimodal imaging in Uveitis (MUV) Taskforce: Report 17.

Ophthalmology. Retina·2026
Same author

Case Report: Longitudinal analysis of local immunoregulatory mediators in a DLBCL vitreoretinal lymphoma receiving local chemotherapy.

Frontiers in medicine·2026
Same author

Response to letter to the editor: modified flapless surgical technique for sutureless scleral fixation of FIL SSF intraocular lens.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2026
Same author

Toxoplasma gondii retinochoroiditis associated with Epstein-Barr virus-induced retinal necrosis in an immunocompetent patient.

Journal of ophthalmic inflammation and infection·2026
Same author

Evidence and Consensus-Based Guidelines in Vogt-Koyanagi-Harada Disease. Multimodal Imaging in Uveitis (MUV) Taskforce Report 16.

Ophthalmology. Retina·2026
Same author

Choroidal abnormalities: the new hallmark ocular finding in neurofibromatosis type 1.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026

Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Biomedical Engineering

Background:

  • Optical coherence tomography (OCT) has become a cornerstone in ophthalmology for in vivo imaging of the retina and optic nerve head.
  • The widespread adoption of OCT has significantly altered diagnostic strategies for retinal diseases.
  • Current clinical practice primarily utilizes time-domain OCT for retinal depth information acquisition.

Purpose of the Study:

  • To review recent advancements in Optical Coherence Tomography (OCT) imaging.
  • To focus on the latest developments and applications of OCT in retinal imaging.
  • To explore emerging functional OCT techniques and contrast-enhanced molecular imaging.

Main Methods:

  • Review of recent literature on OCT advancements.

More Related Videos

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
08:17

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo

Published on: September 22, 2017

Related Experiment Videos

Last Updated: Jul 18, 2026

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy
08:22

Application of Optical Coherence Tomography to a Mouse Model of Retinopathy

Published on: January 12, 2022

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
08:17

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo

Published on: September 22, 2017

  • Discussion of ultrahigh resolution OCT and spectral-domain OCT.
  • Exploration of functional OCT techniques like polarization-sensitive OCT.
  • Overview of contrast-enhanced molecular optical imaging with nanoparticles.

    • Main Results:

    • Significant improvements in OCT image resolution, speed, signal-to-noise ratio, and sensitivity have been achieved.
    • Functional OCT techniques enable assessment of retinal nerve fiber layer thickness and oxygenation.
    • Emerging contrast-enhanced molecular imaging shows promise for targeted tissue and cell structure visualization.

    Conclusions:

    • OCT technology continues to evolve rapidly, offering enhanced diagnostic capabilities for retinal conditions.
    • Functional OCT and molecular imaging represent the next frontier, promising more detailed insights into retinal physiology and pathology.
    • These advancements are poised to further refine diagnostic strategies and treatment monitoring in ophthalmology.