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Published on: April 7, 2023
[The investigation of FFA fixative solution for retina]
Wenxin Zhang1, Yongping Li, Jianxian Lin
1Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China. zoc201@yahoo.com
Purpose:
To search for an effective fixative solution for retina.
Methods:
One group of retinas were fixed in an admixture of formalin, dehydrated alcohol and glacial acetic acid (FFA). The other group of retinas were fixed in 10% neutral formalin.HE and immunohistochemistry were performed. Then compare the difference under the light microscope.
Results:
The structure of the retinas fixed in FFA fixative solution was clear. The cells were arranged and compacted. Few exfoliation of the tissue from the glass slide was observed.
Conclusion:
FFA fixative solution is superior to 10% neutral formalin for the fixation of retina.

