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Updated: Jul 18, 2026

Multifocal Electroretinograms
Published on: December 4, 2011
[Comparative analysis of first and second order kernels of multifocal retinogram in normal subjects]
Guangwei Luo1, Futian Jiang, Shixian Long
1Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, China.
Purpose:
To compare the features of waveform and retinal distribution between first order kernel (FOK) and second order kernel (SOK) of multifocal electro retinogram (mfERG) in normal subjects.
Methods:
The mfERG were recorded in 17 normal eyes. The recordings were finished by the VERIS Science 4.0 system, with the condition of 96% contrast and 103 hexagons stimulating pattern.
Results:
Compared with the FOK, the waveform of SOK was complex with more wavelets. Generally, there were 3 positive and 3 negative waves in the first slice of SOK, and 4 positive and 4 negative in the second slice of SOK. Except the latencies, the retinal distributions of amplitude responses of FOK and SOK were almost the same as the following. The amplitude densities from central hexagon were the highest, and gradually decreased as the acentric degree increased. The amplitudes were larger in upper and temporal retina than those of lower and nasal retina. But the total energy of it was much smaller than that of FOK.
Conclusions:
The features of retinal distribution of SOK were almost the same as FOK in normal people. It needs further research on whether it has the specificity for some kinds of fundus diseases or not.

