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Updated: Jul 18, 2026
Immunolabeling and Counting Ribbon Synapses in Young Adult and Aged Gerbil Cochleae
Published on: April 21, 2022
[Expression of BDNF and trk B in the cochleas of the aged rats]
Yuru Li1, Delong Liu, Yuanyuan Zhang
1Department of Otolaryngology, First Hospital of Harbin Medical University, Harbin 150001, China.
Objective:
To explore the correlation between the expression of brain derived neurotrophic factor (BDNF) and presbycusis in the cochleae of the aged rats.
Method:
The mRNA expression of BDNF and presbycusis in the cochleas of the aged rats was quantitated by real time PCR.
Result:
The expression of BDNF in the cochleas of the aged rats with presbycusis was obviously less than that in the control group. And the difference was statistically significant.
Conclusion:
The expression of BDNF is closely correlated to presbycusis in the aged rats.
