Persistent and progressive ST segment elevation caused by myocardial metastasis
Ante Matana1, Luka Zaputović, Ksenija Lucin
1Department of Internal Medicine, Division of Cardiology, Clinical Hospital Center Rijeka, Rijeka, Croatia. interna-susak@kbc-rijeka.hr
Tumori
|December 16, 2006
Insights
Collecting duct carcinoma, a rare kidney cancer, can spread to the heart. This case highlights the electrocardiogram (ECG) changes associated with myocardial metastasis from kidney cancer.
Area of Science:
- Cardiovascular Pathology
- Nephrology
- Oncology
Background:
- Collecting duct carcinoma is an aggressive renal neoplasm with a propensity for metastasis.
- Myocardial metastasis from renal tumors is exceptionally rare.
Observation:
- A female patient presented with electrocardiogram (ECG) abnormalities including prolonged ST elevation and decreasing R wave amplitude in precordial leads (V3-V6).
- These ECG findings were indicative of myocardial involvement.
Findings:
- Autopsy confirmed metastatic collecting duct carcinoma of the right kidney involving the myocardium.
- The observed ECG changes correlated with the extent of myocardial infiltration.
Implications:
- This case underscores the importance of considering metastatic disease in the differential diagnosis of cardiac abnormalities, even in the absence of typical cardiac symptoms.
- Awareness of such rare presentations can aid in earlier diagnosis and management of advanced renal cell carcinoma.
Abstract:
This is a case of a female patient with collecting duct carcinoma of the right kidney and myocardial metastasis. On electrocardiogram the myocardial metastasis presented with a prolonged and progressive ST elevation and a gradual decrease of the R wave amplitude in leads V3-V6. Echocardiography and autopsy findings confirmed the diagnosis.
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