Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Geometric self-sorting in DNA self-assembly.

Yu He¹, Ye Tian, Yi Chen

¹Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA.

Chemical Communications (Cambridge, England)

|December 21, 2006

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

<i>In Situ</i> Imaging of Nanorod Adsorption and Assembly at Liquid Surfaces.

ACS nano·2026

Same author

Revisiting the Conformational Flexibility of DNA 3-Arm Junctions for Nanoconstruction.

Nano letters·2026

Same author

Assembly of Protein-DNA Framework Nanostructures: Structurally Defining Protein-DNA Interfaces With Aptamer.

Angewandte Chemie (International ed. in English)·2026

Same author

Fluorogenic Aptamer Optimization on a Massively Parallel Sequencing Platform.

ACS sensors·2026

Same author

Lifetime-based multiplexed detection of viral RNA using fluorogenic aptamers.

bioRxiv : the preprint server for biology·2026

Same author

Programmable Synthesis of DNA Networks in Giant Vesicles via Rolling Circle Amplification.

Nano letters·2026

Same journal

An intrinsically stretchable nanowire-based sensing patch for wearable analysis of sweat chloride ion composition.

Chemical communications (Cambridge, England)·2026

Same journal

A sterically rigid-flexible balanced NHC-Pd precatalyst for room-temperature solvent-free C-N coupling of benzocyclic amines.

Chemical communications (Cambridge, England)·2026

Same journal

Portable fluorescent conjugated microporous polymer sensor coupled with a smartphone for on-site Fe<sup>3+</sup> detection in water.

Chemical communications (Cambridge, England)·2026

Same journal

Accelerated discovery of NO<sub>3</sub>RR single-atom catalysts <i>via</i> high-throughput DFT and machine learning.

Chemical communications (Cambridge, England)·2026

Same journal

Wafer-scale robust graphene electronics under industrial processing conditions.

Chemical communications (Cambridge, England)·2026

Same journal

Subnanoscale IrW oxide anodes: breaking immiscibility for high activity and durability in water electrolysis.

Chemical communications (Cambridge, England)·2026

See all related articles

Two DNA star motifs self-assemble into 2D arrays by recognizing and binding only to identical motifs. This selective self-assembly occurs despite identical local interaction rules between all motif types, demonstrating programmable specificity in DNA nanotechnology.

Area of Science:

Biochemistry
Materials Science
Nanotechnology

Background:

DNA self-assembly is a powerful tool for creating nanoscale structures.
Designing specific recognition and exclusion rules is crucial for complex array formation.

Purpose of the Study:

To investigate the self-assembly behavior of two distinct DNA star motifs.
To understand the mechanism of selective recognition and exclusion in 2D array formation.

Main Methods:

Utilizing DNA star motifs with specific binding domains.
Observing self-assembly through microscopy or other relevant imaging techniques.

Main Results:

Two types of DNA star motifs selectively associate with like motifs.

Related Experiment Videos

The motifs successfully form ordered 2D arrays composed of homogeneous tile types.

Unlike motifs were excluded from forming mixed arrays.

Conclusions:

Selective self-assembly of DNA motifs can be achieved by designing specific recognition properties.
This system demonstrates programmable control over nanoscale structure formation, excluding non-cognate interactions.