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Updated: Jul 18, 2026

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System for Focal, Closed-System Central Nervous System Injury
Published on: November 29, 2024
Traumatic unilateral internuclear ophthalmoplegia.
1Department of Ophthalmology, Loyola University Medical Center, Maywood, Illinois 60153, USA.
Seminars in Ophthalmology
|December 22, 2006
Summary
A traumatic brain injury led to internuclear ophthalmoplegia in a young man. This rare condition, often caused by trauma, showed significant improvement over time.
Area of Science:
- Neuroscience
- Ophthalmology
- Trauma Surgery
Background:
- A 23-year-old male sustained a closed head injury from a fall, resulting in a C-7 burst fracture.
- A halo and halo vest were applied 9 hours post-injury for spinal stabilization.
Observation:
- The patient developed diplopia 21 hours after the accident.
- Neuro-ophthalmology evaluation revealed unilateral internuclear ophthalmoplegia.
- Brain MRI showed a small infarct in the inferior midbrain.
Findings:
- The patient experienced 90% improvement in internuclear ophthalmoplegia by 9.5 weeks.
- Literature review indicates traumatic internuclear ophthalmoplegia predominantly affects males (83.33%) with a mean age of 31.7.
- Common causes include motor vehicle accidents (41.79%) and blunt trauma (16.42%).
Implications:
- This case highlights a rare complication of head trauma and spinal injury.
- Early diagnosis and management are crucial for visual recovery.
- Further research into the mechanisms and treatment of traumatic internuclear ophthalmoplegia is warranted.
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