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Obstetric cerebral venous thrombosis

Bhojo A Khealani1, Uzma U Mapari, Rozina Sikandar

  • 1Neurology Section, Department of Medicine, The Aga Khan University, Karachi.

JPMA. the Journal of the Pakistan Medical Association
|December 23, 2006
PubMed

Pregnancy and puerperium are most prevalent prothrombotic states leading to cerebral venous thrombosis. Likelihood of stroke to be of venous origin is greater in stroke associated with pregnancy compared to stroke unrelated to pregnancy. Pregnancy induces several changes in coagulation system, which persists at least during early puerperium, rendering it a prothrombotic state. Hypercoaguability worsens further after delivery as a result of volume depletion and trauma. During puerperium additional risk factors include infection and instrumental delivery or Caesarean section. The management follows general rules as for the venous thrombosis unrelated to pregnancy, however the prognosis is different.

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