Related Experiment Video
Updated: Jul 18, 2026
09:03
Forward Genetic Approaches in Chlamydia trachomatis
Published on: October 23, 2013
[Erythema multiforme majus and Chlamydia pneumoniae infection]
1CHU de Poitiers, Hôpital de la Miletrie, Poitiers. delphine.saada@gmail.com
Annales De Dermatologie Et De Venereologie
|December 23, 2006
Summary
Erythema multiforme majus, a severe skin condition, can be caused by Chlamydia pneumoniae infection. This case highlights the importance of considering this pathogen in diagnosis and treatment.
Area of Science:
- Dermatology
- Infectious Diseases
- Microbiology
Background:
- Erythema multiforme majus (EMM) is an acute eruptive syndrome often seen in young individuals, characterized by target lesions.
- Commonly associated with Herpes simplex virus or Mycoplasma pneumoniae infections.
- This report details an original case of EMM linked to Chlamydia pneumoniae infection.
Observation:
- An 18-year-old male presented with a generalized rash, including oral and genital lesions, accompanied by fever and cough.
- Initial investigations suspected various bacterial and viral agents.
- Serological testing confirmed Chlamydia pneumoniae infection (IgM 128 IU, IgG 64 IU), while Mycoplasma pneumoniae remained negative.
Findings:
- The patient's diagnosis of EMM was supported by characteristic target and mucosal lesions, with other causes ruled out.
- Positive serological tests for Chlamydia pneumoniae (IgM and IgG) at multiple time points confirmed the etiological link.
- Treatment with symptomatic care and antibiotics (acyclovir, ofloxacin) led to a favorable outcome.
Implications:
- This case underscores Chlamydia pneumoniae as a potential cause of erythema multiforme majus.
- Dermatologists should consider Chlamydia pneumoniae in EMM diagnosis, especially when common causes are excluded.
- Accurate etiological diagnosis is crucial for optimizing patient treatment and management.
Related Concept Videos
01:14Atypical Pneumonia
Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
01:29Bacterial Phylum Chlamydiae
The phylum Chlamydiae or Chlamydiota is composed of a single order, Chlamydiales. This phylum consists entirely of obligate intracellular parasites that infect eukaryotic hosts. While human pathogens within this group have been studied extensively, the phylum encompasses many species capable of interacting with various eukaryotic organisms. Members of Chlamydiae are typically small cocci, approximately 0.5 μm in diameter, and exhibit a distinctive developmental cycle. As is characteristic of...
01:26Sexually Transmitted Infections
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
01:27Myocarditis II: Clinical Features and Diagnostic Tests
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
01:23Chronic Pharyngitis
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
01:30Acute Pharyngitis
Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause: