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Chronic constipation: advances in management.

A Wald1

  • 1Section of Gastroenterology and Hepatology, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53792, USA. axw@medicine.wisc.edu

Neurogastroenterology and Motility
|December 26, 2006
PubMed
Summary
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This review focuses on refractory functional constipation in patients referred to specialists. It covers pathophysiology, diagnostics, treatments including medications and behavioral therapies, and surgical options.

Area of Science:

  • Gastroenterology
  • Clinical Medicine

Background:

  • Most constipation cases are managed with conservative measures.
  • A subset of patients presents with refractory or difficult-to-manage functional constipation.
  • These complex cases are often referred to gastrointestinal specialists.

Purpose of the Study:

  • To provide insights into the pathophysiology of refractory functional constipation.
  • To evaluate the utility of diagnostic testing in these patients.
  • To discuss pharmacologic agents, behavioral therapies, and surgical interventions.

Main Methods:

  • Literature review and expert opinion.
  • Focus on patients with refractory functional constipation.
  • Analysis of diagnostic approaches and therapeutic options.

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Main Results:

  • Functional constipation pathophysiology is complex.
  • Diagnostic testing aids in management.
  • Pharmacologic and behavioral therapies are key, with surgery as an option.

Conclusions:

  • Refractory functional constipation requires a multifaceted approach.
  • Individualized treatment plans are essential.
  • Gastrointestinal specialists play a crucial role in managing these challenging cases.