Urtica ferox neuropathy
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Updated: Jul 17, 2026

Establishing a Mouse Model of a Pure Small Fiber Neuropathy with the Ultrapotent Agonist of Transient Receptor Potential Vanilloid Type 1
Published on: February 13, 2018
Graeme D Hammond-Tooke1, Peter Taylor, Saman Punchihewa
1Department of Medical and Surgical Sciences, University of Otago Medical School, P.O. Box 913, Dunedin, New Zealand. graemeH@healthotago.co.nz
Abstract:
A 21-year-old student developed an acute, symmetrical, predominantly motor polyneuropathy within 48 h of walking through a patch of nettles (Urtica ferox). Two companions had similar but less severe symptoms. Nerve conduction studies demonstrated markedly reduced compound muscle action potentials and prolonged distal motor latencies. Recovery occurred over a period of a few weeks. This case demonstrates that cutaneous exposure to Urtica ferox can cause an acute polyneuropathy and that its stinging hairs contain an unidentified neurotoxin.
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