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Updated: Jul 17, 2026

Measurements of Motor Function and Other Clinical Outcome Parameters in Ambulant Children with Duchenne Muscular Dystrophy
Published on: January 12, 2019
Recommendations to define exercise prescription for Duchenne muscular dystrophy
Robert W Grange1, Jarrod A Call
1Department of Human Nutrition, Foods and Exercise, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0430, USA. rgrange@vt.edu
Abstract:
Duchenne muscular dystrophy yields pervasive and progressive muscle weakness. This weakness may be attenuated by regular, low-intensity exercise. However, there is a critical lack of data to support appropriate exercise prescription. Because inappropriate activity may exacerbate the dystrophic process, a systematic analysis of muscle function to determine potential exercise load thresholds to avoid injury in dystrophic mice and dogs, and then in humans, is recommended.
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