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Cleistanthus collinus poisoning.

S P E Benjamin1, M Edwin Fernando, J Jerene Jayanth

  • 1Departments of Medicine and Nephrology, CSI Kalyani Multispeciality Hospital, Mylapore, Chennai.

The Journal of the Association of Physicians of India
|January 11, 2007
PubMed
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Ingesting Cleistanthus collinus leaves can cause severe poisoning. This case highlights acute respiratory distress syndrome and renal tubular acidosis from this toxic plant.

Area of Science:

  • Toxicology
  • Cardiology
  • Nephrology

Background:

  • Cleistanthus collinus is a highly toxic plant containing diphyllin glycosides, cleistanthin A and B.
  • These toxins are known to cause cardiac arrhythmias, urinary potassium wasting, hypoxia, metabolic acidosis, and hypotension.

Observation:

  • A case of severe poisoning following ingestion of Cleistanthus collinus leaves is presented.
  • The patient developed acute respiratory distress syndrome (ARDS) and distal renal tubular acidosis.

Findings:

  • The poisoning resulted in distributive shock attributed to inappropriate vasodilation.
  • The clinical presentation included severe metabolic disturbances and organ dysfunction.

Implications:

Related Experiment Videos

  • This case underscores the extreme toxicity of Cleistanthus collinus and the potential for severe, multi-organ complications.
  • Early recognition and management of Cleistanthus collinus poisoning are crucial for patient outcomes.