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Related Experiment Video

Updated: Jul 17, 2026

A Mouse Distraction Osteogenesis Model
04:24

A Mouse Distraction Osteogenesis Model

Published on: November 14, 2018

Distraction osteogenesis in a severe mandibular deficiency.

Kerim Ortakoglu1, Seniz Karacay, Metin Sencimen

  • 1Department of Oral and Maxillofacial Surgery, Gulhane Military Medical Academy, Ankara, Turkiye. kortakoglu@yahoo.com

Head & Face Medicine
|January 24, 2007
PubMed
Summary

Distraction osteogenesis successfully lengthened a severely hypoplastic mandible, improving facial aesthetics and function. This innovative treatment corrected significant overjet and enhanced airway space.

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Area of Science:

  • Oral and Maxillofacial Surgery
  • Orthodontics
  • Craniofacial Reconstruction

Background:

  • Mandibular hypoplasia presents significant aesthetic and functional challenges.
  • Distraction osteogenesis offers a reconstructive approach for severe skeletal discrepancies.

Observation:

  • A case report details the use of a multidirectional extraoral device for mandibular lengthening.
  • Bilateral distraction osteogenesis of the ramus and corpus was performed.
  • A 7-day latency period was followed by gradual distraction and a 12-week consolidation phase.

Findings:

  • Cephalometric analysis showed a decrease in ANB angle from 13 to 6 degrees and overjet from 15 mm to 4 mm.
  • Mandibular corpus length increased from 49 mm to 67 mm, and ramus length from 41 mm to 43 mm.

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  • Posterior airway space (PAS) and craniofacial dimensions improved post-distraction.

    • Implications:

    • Distraction osteogenesis is a viable treatment for severe mandibular hypoplasia.
    • This technique yields significant functional and aesthetic improvements.
    • Further research can explore long-term outcomes and device variations.