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[Pet-rat bite fever and septic arthritis: molecular identification of Streptobacillus moniliformis]

S Mignard1, B Aubry-Rozier, M de Montclos

  • 1Laboratoire de bactériologie, centre hospitalier Lyon Sud, chemin du Grand-Revoyet, 69495 Pierre-Bénite, France. sophie.mignard@chu-lyon.fr

Medecine Et Maladies Infectieuses
|January 30, 2007
PubMed

Insights

Pet rat bites can cause a rare illness called rat bite fever. A case of septic arthritis caused by Streptobacillus moniliformis was successfully treated with amoxicillin.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Rheumatology

Background:

  • Pet rat ownership is common, but rat bite fever remains a rare zoonotic disease.
  • Septic arthritis is a serious joint infection that requires prompt diagnosis and treatment.

Observation:

  • A case of septic arthritis following a pet rat bite is presented.
  • Streptobacillus moniliformis was identified in the patient's knee synovial fluid.

Findings:

  • 16S rRNA sequencing proved to be a rapid and efficient method for identifying the fastidious bacterium.
  • The patient achieved a full recovery following amoxicillin treatment.

Implications:

  • This case highlights the importance of considering rat bite fever in patients with septic arthritis after rat exposure.
  • 16S rRNA sequencing is a valuable diagnostic tool for identifying unusual bacterial pathogens.
  • Amoxicillin is an effective treatment for Streptobacillus moniliformis infections.

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