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MRI-guided Focused Ultrasound Thalamotomy for Patients with Medically-refractory Essential Tremor
Published on: December 13, 2017
[Posttraumatic hyperkinésie volitionnelle was markedly improved by Vim thalamic deep brain stimulation]
Yuhei Takado1, Takayoshi Shimohata, Kenshi Terajima
1Department of Neurology, Brain Research Institute, Niigata University.
Rinsho Shinkeigaku = Clinical Neurology
|January 31, 2007
Summary
Traumatic brain injury can cause hyperkinésie volitionnelle (HV), a tremor type, even with intact cerebellar pathways. Vim deep brain stimulation (DBS) effectively treated drug-resistant HV in this case.
Area of Science:
- Neuroscience
- Neurology
- Neurosurgery
Background:
- Hyperkinésie volitionnelle (HV) is a rare movement disorder.
- Traumatic brain injury (TBI) can lead to various neurological deficits, including movement disorders.
Observation:
- A 69-year-old male presented with HV one year post-TBI.
- Standard neuroimaging and electrophysiological tests, including 3D anisotropy contrast magnetic resonance axonography (3DAC-MRX) and movement-related cortical potential (MRCP), showed no abnormalities.
- This suggested intact cerebellar efferent pathways.
Findings:
- Despite normal findings in imaging and electrophysiology, the patient exhibited tremor-type HV.
- Vim deep brain stimulation (DBS) significantly alleviated HV symptoms.
- The patient's HV was resistant to clonazepam treatment.
Implications:
- This case suggests TBI can induce tremor-type HV even with preserved cerebellar efferent pathways.
- Vim DBS presents a viable therapeutic option for drug-resistant HV following TBI.
- Further research into the pathophysiology of TBI-induced movement disorders is warranted.
