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Updated: Jul 17, 2026
10:39
Heterogeneous Removal of Water-Soluble Ruthenium Olefin Metathesis Catalyst from Aqueous Media Via Host-Guest Interaction
Published on: August 23, 2018
Reversible guest exchange mechanisms in supramolecular host-guest assemblies
Michael D Pluth1, Kenneth N Raymond
1University of California, Department of Chemistry, Berkeley, CA 94720, USA.
Chemical Society Reviews
|February 1, 2007
Summary
Synthetic chemists create supramolecular host molecules for reversible polyatomic guest encapsulation. This review details guest exchange mechanisms and monitoring techniques, focusing on constrictive binding in various assemblies.
Area of Science:
- Supramolecular Chemistry
- Host-Guest Chemistry
Background:
- Synthetic chemists have developed diverse supramolecular assemblies capable of encapsulating guest molecules.
- Reversible encapsulation of polyatomic guests by supramolecular hosts is a key area of research.
Purpose of the Study:
- To review supramolecular host molecules that reversibly encapsulate polyatomic guests.
- To explore the mechanisms of guest encapsulation and release.
- To discuss methods for monitoring and characterizing guest exchange.
Main Methods:
- Nuclear Magnetic Resonance (NMR) spectroscopy
- UV-Visible (UV-VIS) spectroscopy
- Mass spectrometry
- Electrochemistry
- Calorimetry
Main Results:
- Common methods for monitoring guest exchange are presented.
- Representative examples of guest exchange mechanisms are discussed.
- Focus on constrictive binding, a common motif in guest exchange systems.
Conclusions:
- Guest exchange mechanisms in hemicarcerands, cucurbiturils, hydrogen-bonded assemblies, and metal-ligand assemblies are analyzed.
- Understanding these mechanisms is crucial for designing advanced supramolecular systems.
- Constrictive binding plays a significant role in supramolecular guest exchange dynamics.
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