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Updated: Jul 17, 2026

Isolation and Selection of Entomopathogenic Fungi from Soil Samples and Evaluation of Fungal Virulence against Insect Pests
Published on: September 28, 2021
New diphenyl ethers from the insect pathogenic fungus Cordyceps sp. BCC 1861
Taridaporn Bunyapaiboonsri1, Seangaroon Yoiprommarat, Kamolphan Intereya
1National Center for Genetic Engineering and Biotechnology (BIOTEC), Klong Luang, Pathumthani, Thiland. taridaporn@biotech.or.th
Abstract:
Two novel diphenyl ether glycosides and a new diphenyl ether, cordyol A-C (1-3), were isolated from the insect pathogenic fungus Cordyceps sp. BCC 1861. Structures of these compounds were elucidated by NMR and MS spectral analyses. Cordyol C (3) exhibited significant anti-HSV-1 activity with an IC50 value of 1.3 microg/ml, and cytotoxic activity against BC and NCI-H187 cancer cell lines with IC50 values of 8.65 and 3.72 microg/ml, respectively. Cordyol A (1) displayed weak antimycobacterial activity with a MIC value of 100 microg/ml.
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