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Transcutaneous Microcirculatory Imaging in Preterm Neonates
Published on: December 31, 2015
Glanzmann thrombasthenia in a neonate
Aysegul Zenciroglu1, Ahmet Yagmur Bas, Nihal Demirel
1Department of Neonatology, and Pediatric Hematology, Dr. Sami Ulus Childrens Hospital, Ankara, Turkey.
Indian Pediatrics
|February 6, 2007
Summary
Glanzmann thrombasthenia, a rare bleeding disorder, was diagnosed in a six-day-old newborn, the youngest reported case. This qualitative platelet defect causes significant bleeding complications from birth.
Area of Science:
- Hematology
- Pediatric Medicine
- Genetics
Background:
- Glanzmann thrombasthenia is an inherited qualitative platelet function disorder.
- It is characterized by impaired platelet aggregation, leading to a lifelong bleeding tendency.
- Manifestations include mucocutaneous bleeding, epistaxis, and gastrointestinal hemorrhage.
Observation:
- A six-day-old newborn presented with hematuria after suprapubic aspiration.
- Clinical evaluation and laboratory tests were performed to investigate the cause of bleeding.
Findings:
- The newborn was diagnosed with Glanzmann thrombasthenia.
- This represents the youngest reported case of Glanzmann thrombasthenia in the medical literature.
- The diagnosis highlights the potential for early-onset presentation of this disorder.
Implications:
- Early diagnosis of Glanzmann thrombasthenia in neonates is crucial for timely management.
- This case underscores the importance of considering rare bleeding disorders in newborns with unexplained hemorrhage.
- Further research into neonatal Glanzmann thrombasthenia may improve diagnostic and therapeutic strategies.
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