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Chromatographic Fingerprinting by Template Matching for Data Collected by Comprehensive Two-Dimensional Gas Chromatography
Published on: September 2, 2020
Two-dimensional correlation analysis useful for spectroscopy, chromatography, and other analytical measurements
1The Procter & Gamble Company, West Chester, Ohio 45069, USA. noda.i@pg.com
Summary
Generalized two-dimensional (2D) correlation spectroscopy and chromatography reveal coordinated signal changes. This powerful analytical technique enhances resolution and determines the sequence of intensity variations under external perturbations.
Area of Science:
- Analytical Chemistry
- Spectroscopy
- Chromatography
Background:
- Generalized two-dimensional (2D) correlation is a versatile analytical technique.
- It is applicable to various measurements, including spectroscopy and chromatography.
- The method requires a series of analytical signals systematically varied by an external perturbation.
Purpose of the Study:
- To explore the application of generalized 2D correlation in analytical fields.
- To demonstrate the utility of 2D correlation for analyzing complex systems.
- To highlight the benefits of 2D correlation in enhancing signal resolution and determining sequential information.
Main Methods:
- Collecting a series of analytical signals (e.g., spectra, chromatograms) under an external perturbation.
- Applying generalized two-dimensional (2D) correlation analysis to the collected signals.
- Perturbations include changes in temperature, pressure, concentration, or chemical/physical stimuli.
Main Results:
- 2D correlation spectra provide insights into coordinated or independent signal changes.
- The technique reveals the relative directions and sequential order of signal intensity variations.
- Overlapped bands are spread along the second dimension, enhancing signal resolution.
Conclusions:
- Generalized 2D correlation is a powerful tool for analyzing complex analytical data.
- It offers enhanced resolution and provides detailed information on signal dynamics.
- The technique is broadly applicable across spectroscopy and chromatography.
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