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[Gaseous messengers in the nervous system]
Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova
|February 16, 2007
Summary
Gaseous messengers like nitric oxide, carbon monoxide, and hydrogen sulfide play vital roles in the nervous system. This review consolidates current knowledge on their functions and mechanisms in both central and peripheral nervous systems.
Area of Science:
- Neuroscience
- Physiology
- Biochemistry
Context:
- Gaseous signaling molecules are crucial in biological systems.
- Nitric oxide (NO) is a well-studied gaseous messenger.
- Emerging research highlights carbon monoxide (CO) and hydrogen sulfide (H2S) roles.
Purpose:
- To review the current understanding of gaseous messengers in the nervous system.
- To explore the physiological roles and mechanisms of NO, CO, and H2S.
- To identify gaps in knowledge regarding gasotransmitters in neural functions.
Summary:
- Nitric oxide, carbon monoxide, and hydrogen sulfide act as endogenous gaseous messengers.
- Their functions are established in the gastrointestinal and cardiovascular systems.
- This article focuses on their insufficient explored roles within the central and peripheral nervous systems.
Impact:
- Provides a consolidated overview of gasotransmitter functions in neuroscience.
- Highlights the need for further research into their neural mechanisms.
- Facilitates understanding of novel therapeutic targets for neurological disorders.
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