Long-term optical quality of the photoablated cornea

High-order coreal wavefront analysis was performed in a population of 60 myopic eyes that underwent photorefractive keratectomy. Corneal aberration data over 3, 5, and 7 mm pupils were collected for up to three years after surgery. The optical performance of the anterior cornea was characterized by estimation of the modulation transfer function (MTF) and the point-spread function. The high-order corneal wavefront aberrations were shown to stabilize one year after surgery. Over photopic pupils, after an early slight increase, corneal RMS-high-order aberrations (HOA) tended to decrease toward preoperative values. On the other hand, over mid- and large-pupil sizes, corneal HOA significantly increased compared with the preoperative state, while the optical performance of the cornea was diminished. The MTF ratio showed a distinct decline in the optical quality of postoperative corneas at low and middle spatial frequencies over larger pupils in the range between 6 and 19 c/deg, especially for deeper ablations.