[Pneumonia with septicemia caused by Pasteurella multocida in an immunocompetent patient]
E Pukenyte1, S Nguyen, R Le Berre
1Service universitaire des maladies infectieuses et du voyageur, centre hospitalier de Tourcoing, 59208 Tourcoing, France.
Abstract:
Pneumonia with septicemia caused by Pasteurella multocida was diagnosed in an immunocompetent patient exposed to a dog. This case is remarkable by two aspects: first the absence of visible cutaneous lesion, and second the localization and severity of the infection caused by P. multocida even though the patient was immunocompetent. P. multocida can cause respiratory and systemic infection, and it is a possible diagnosis in case of exposure to animals, even without history of bite or scratch. Furthermore, severe infections caused by this pathogen can occur in immunocompetent patients, so that the implication of specific host factors in the severity of the disease can be suspected. Genetic features could be one of these.
Insights
Severe Pasteurella multocida infections, including pneumonia and septicemia, can occur in immunocompetent individuals after dog exposure, even without skin lesions. Host genetic factors may influence disease severity.
Area of Science:
- Infectious Diseases
- Microbiology
- Immunology
Background:
- Pasteurella multocida is a bacterium commonly found in animals.
- It can cause various infections in humans, particularly after animal contact.
- Severe systemic infections are typically associated with immunocompromised individuals.
Observation:
- A case of pneumonia and septicemia caused by Pasteurella multocida in an immunocompetent patient with dog exposure.
- The patient presented with no visible skin lesions.
- The infection was severe and systemically localized.
Findings:
- Pasteurella multocida can cause severe respiratory and systemic infections in immunocompetent hosts.
- Absence of bite or scratch marks does not rule out Pasteurella multocida infection following animal exposure.
- The severity of Pasteurella multocida infections in immunocompetent individuals suggests potential host-specific factors.
Implications:
- Clinicians should consider Pasteurella multocida in the differential diagnosis of severe infections in patients with animal exposure, irrespective of skin lesions.
- Further research into host genetic factors is warranted to understand the variability in disease severity.
- This case highlights the potential for zoonotic transmission of severe bacterial infections.
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