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Moderate exercise-induced energy expenditure does not alter leptin levels in sedentary obese men
George A Kyriazis1, Jonathan D Caplan, Joshua Lowndes
1Center for Lifestyle Medicine and Department of Health Professions, University of Central Florida, 12201 Research Parkway, Orlando, FL 32826, USA.
Objective:
The purpose of the study was to determine whether exercise-induced increases in energy expenditure (EE) alter circulating leptin levels in obese individuals.
Design:
Participants were randomized to an exercise intervention group (n = 8) or nonexercising control (n = 7).
Setting:
All data were collected on an outpatient basis at the exercise physiology laboratory at the University of Central Florida.
Patients:
Fifteen healthy obese males (24.9 +/- 1.4 years old, body mass index 33.4 +/- 0.7 kg . m).
Interventions:
Members of the intervention group underwent a single exercise session of moderate intensity (58.4 +/- 1.3% of VO2max) for 60 minutes.
Main Outcome Measurements:
Postexercise, 24 hour postexercise, and 48 hour postexercise levels of leptin, insulin, and ghrelin.
Results:
The exercise session elicited an EE of 567 +/- 25 Kcal. No significant main effect or time-by-group interactions for leptin or ghrelin were observed immediately after the exercise bout or in the days following the intervention.
Conclusions:
These preliminary data suggest that a bout of acute exercise of moderate intensity and duration does not affect leptin concentration. It is possible that a higher level of EE is required to elicit substantial changes.
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