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Infectious neuropathies.

Gérard Said1

  • 1Service de Neurologie, Hôpital de Bicêtre, Université Paris XI, 94275 Le Kremlin Bicêtre, France. gerard.said@bct.aphp.fr

Neurologic Clinics
|February 28, 2007
PubMed
Summary
This summary is machine-generated.

Infective agents like viruses, parasites, and bacilli can cause peripheral neuropathies. Fortunately, these conditions, including those linked to HIV and Lyme disease, are treatable and often preventable.

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Area of Science:

  • Neurology
  • Infectious Diseases

Background:

  • Peripheral neuropathies are a diverse group of disorders affecting the nerves outside the brain and spinal cord.
  • Infective agents, including viruses (e.g., retroviruses), parasites, and bacilli, are significant causes of peripheral neuropathies.
  • Conditions like leprosy, Human Immunodeficiency Virus (HIV) infection, and Lyme disease contribute to the global burden of neuropathies.

Purpose of the Study:

  • To highlight the etiological role of various infective agents in peripheral neuropathies.
  • To emphasize the continued prevalence of certain neuropathies, such as leprosy, in specific geographic regions.
  • To underscore the treatability and preventability of these neurological conditions.

Main Methods:

  • Review of literature on infectious causes of peripheral neuropathies.

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  • Analysis of epidemiological data concerning leprosy, HIV, and Lyme disease-associated neuropathies.
  • Synthesis of information on current treatment and prevention strategies.

    • Main Results:

    • Identified a range of infective agents responsible for peripheral neuropathies.
    • Noted the persistent occurrence of leprosy in Africa, South America, and Asia.
    • Observed an increase in neuropathies among patients with HIV and Lyme disease.

    Conclusions:

    • Peripheral neuropathies stemming from infections are a significant clinical concern.
    • Despite being historically associated with the past, leprosy remains prevalent in endemic areas.
    • Prompt diagnosis and treatment are crucial as these neuropathies are often manageable and preventable.