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Fermented infant formulae without live bacteria.

Carlo Agostoni1, Olivier Goulet, Sanja Kolacek

  • 1San Paolo Hospital, University of Milan, Milan, Italy.

Journal of Pediatric Gastroenterology and Nutrition
|February 28, 2007
PubMed
Summary
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Fermented infant formulas, despite containing no live bacteria, show potential in reducing infectious diarrhea. More research is needed to confirm these effects and draw broader conclusions on their use.

Area of Science:

  • Pediatric Nutrition
  • Gastroenterology
  • Microbiology

Background:

  • Fermented infant and follow-on formulas undergo bacterial inactivation during processing.
  • Limited clinical data exists on the effects of these fermented products.

Purpose of the Study:

  • To review published information on the clinical evaluation of fermented infant formulas.
  • To assess the current evidence regarding their safety and efficacy.

Main Methods:

  • A systematic literature review was conducted.
  • Two randomized clinical trials involving 933 infants were identified and analyzed.

Main Results:

  • Limited published data is available on fermented infant formulas.

Related Experiment Videos

  • Two studies suggest a potential reduction in infectious diarrhea occurrence or severity.

    • Conclusions:

    • Available data is insufficient for general conclusions on fermented infant formula use.
    • Further randomized controlled trials are recommended to assess effects on infectious diarrhea and other outcomes.