Related Experiment Video
Updated: Jul 16, 2026
05:46
Ultrasonic-Assisted Extraction of Cannabidiolic Acid from Cannabis Biomass
Published on: May 27, 2022
[Cannabis and cannabinoids as drugs]
Hassan Z Khiabani1, Jørg Mørland
1Nasjonalt folkehelseinstitutt, Divisjon for rettstoksikologi og rusmiddelforskning, Postboks 4404 Nydalen, 0403 Oslo. hassan.khiabani@fhi.no
Summary
Cannabinoids, like Delta-9-tetrahydrocannabinol (THC), interact with receptors in the body, offering potential therapeutic uses. However, cannabis use also carries risks such as impaired cognition and psychosis.
Area of Science:
- Pharmacology
- Neuroscience
- Cannabinoid Science
Background:
- Cannabis has a long history of human use.
- Delta-9-tetrahydrocannabinol (THC) is the main psychoactive compound in cannabis.
- THC is metabolized into 11-OH-THC and then to an inactive metabolite, THC-acid.
Purpose of the Study:
- To provide an overview of cannabinoid pharmacokinetics.
- To emphasize the pharmacodynamics of cannabinoids.
- To explore the therapeutic potential of cannabinoids.
Main Methods:
- Literature review.
- Emphasis on cannabinoid pharmacodynamics.
Main Results:
- Mammalian tissues possess cannabinoid receptors (CB1, CB2, and likely CB3) and endogenous ligands.
- Development of CB-agonists and CB-antagonists based on receptor knowledge.
- Potential for studying therapeutic effects of cannabinoids.
Conclusions:
- Cannabinoid receptor knowledge facilitates the development of therapeutic agents.
- Potential therapeutic applications of cannabinoids warrant further investigation.
- Negative effects of cannabis, including cognitive impairment and psychosis risk, must be considered alongside therapeutic potential.
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