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Related Concept Videos

CNS Stimulants: Cocaine, Amphetamines and Cannabinoids01:24

CNS Stimulants: Cocaine, Amphetamines and Cannabinoids

CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its effects by...
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids01:21

Chemotherapy-Induced Nausea and Vomiting: Cannabinoids

Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
Two synthetic agonists of THC,...
Hallucinogens and Psychedelics01:27

Hallucinogens and Psychedelics

Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains delta-9-tetrahydrocannabinol (THC)...
An Overview of Psychoactive Drugs01:28

An Overview of Psychoactive Drugs

Psychoactive drugs impact brain function, influencing perception, mood, consciousness, cognition, and behavior. These substances are grouped based on their effects and the mechanisms by which they act.
Stimulants such as cocaine, amphetamines, and nicotine enhance brain activity, leading to increased alertness, attention, and energy. These drugs typically raise heart rate, blood pressure, and body temperature. While they can induce feelings of euphoria, their misuse can result in severe health...
CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
Depressants01:28

Depressants

Depressant drugs, including alcohol and sedative-hypnotics, diminish central nervous system activity by enhancing the action of gamma-aminobutyric acid (GABA), a neurotransmitter that reduces brain activity and promotes relaxation. These substances can have various therapeutic uses but also pose significant risks, especially when misused or combined.
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...

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Updated: Jul 16, 2026

Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
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Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study

Published on: August 18, 2020

[Cannabis affects driving skills].

Hassan Z Khiabani1, Asbjørg S Christophersen, Jørg Mørland

  • 1Divisjon for rettstoksikologi og rusmiddelforskning, Nasjonalt folkehelseinstitutt, Postboks 4404 Nydalen, 0403 Oslo. hassan.khiabani@fhi.no

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|March 3, 2007
PubMed
Summary

Delta (9)-tetrahydrocannabinol (THC) impairs driving skills, even at low blood concentrations. These cognitive and psychomotor effects can persist longer than THC is detectable, increasing accident risks.

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Driving Under the Influence: How Music Listening Affects Driving Behaviors
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Driving Under the Influence: How Music Listening Affects Driving Behaviors

Published on: March 27, 2019

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Brain Morphology of Cannabis Users With or Without Psychosis: A Pilot MRI Study
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Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
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Driving Under the Influence: How Music Listening Affects Driving Behaviors
07:25

Driving Under the Influence: How Music Listening Affects Driving Behaviors

Published on: March 27, 2019

Area of Science:

  • Forensic toxicology
  • Neuroscience
  • Traffic safety research

Context:

  • Cannabis use is prevalent among drivers.
  • Delta (9)-tetrahydrocannabinol (THC) is the primary psychoactive component of cannabis.
  • Drugged driving is a significant public safety concern.

Purpose:

  • To review the impact of THC on driving fitness.
  • To highlight the risks associated with THC-impaired driving.
  • To emphasize the correlation between THC levels, dose, and impairment.

Summary:

  • THC negatively affects cognitive functions and psychomotor skills essential for driving.
  • Impairment from THC can last beyond the period of measurable blood THC concentrations.
  • Studies show an increased risk of traffic accidents, even with low blood THC levels.

Impact:

  • Findings underscore the importance of addressing cannabis impairment in driving to prevent accidents and fatalities.
  • Highlights the need for effective roadside testing and legal frameworks for drugged driving.
  • Emphasizes the societal costs associated with THC-impaired driving, including economic consequences.