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Puberty moderates genetic influences on disordered eating
Kelly L Klump1, Patrick S Perkins, S Alexandra Burt
1Department of Psychology, Michigan State University, East Lansing, MI 48824-1116, USA. klump@msu.edu
Psychological Medicine
|March 6, 2007
Summary
Puberty increases genetic influences on disordered eating in girls. This suggests that hormonal changes during puberty may activate genes related to disordered eating behaviors.
Area of Science:
- Behavioral genetics
- Adolescent psychology
- Developmental neuroscience
Background:
- Previous research indicates a potential increase in genetic influences on disordered eating during puberty.
- Earlier studies could not directly test if pubertal development moderates these genetic effects.
Purpose of the Study:
- To directly investigate whether pubertal development moderates genetic influences on disordered eating.
- To examine the hypothesis of pubertal activation of genetic predispositions for disordered eating.
Main Methods:
- Study included 510 female adolescent twins from the Minnesota Twin Family Study.
- Disordered eating was assessed using the Minnesota Eating Behavior Survey (MEBS) Total Score.
- Pubertal status was measured using the Pubertal Development Scale (PDS).
Main Results:
- Model-fitting confirmed a significant increase in genetic influence on disordered eating as pubertal development advanced.
- Results support the hypothesis that genetic factors become more prominent with progressing puberty.
Conclusions:
- Pubertal development plays a crucial role in the expression of genes associated with disordered eating.
- These findings highlight the dynamic interplay between genetic vulnerability and developmental stage in disordered eating etiology.
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