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Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells
08:17

Murine Experimental Model of Original Tumor Development and Peritoneal Metastasis via Orthotopic Inoculation with Ovarian Carcinoma Cells

Published on: December 9, 2016

[Intravascular leiomyomatosis: an original tumor]

G Rathat1, P-M Blanc, F Guillon

  • 1Service de gynécologie-obstétrique, CHU Carémeau, place du Professeur-Robert-Debré, 30900 Nîmes, France. gauthier.rathat@wanadoo.fr

Gynecologie, Obstetrique & Fertilite
|March 6, 2007
PubMed

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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...