Related Experiment Video
Updated: Jul 16, 2026

Techniques of Sleeve Gastrectomy and Modified Roux-en-Y Gastric Bypass in Mice
Published on: March 20, 2017
Morbid obesity causes chronic increase of intraabdominal pressure
Eldo E Frezza1, Khaled O Shebani, Jana Robertson
1Division of General Surgery, Department of Surgery, Texas Tech University Health Sciences Center, Lubbock, Texas, USA. eldo.frezza@ttuhsc.edu
Abstract:
Intraabdominal hypertension and the abdominal compartment syndrome are known to deleteriously affect a wide array of organ systems. We retrospectively reviewed 62 women who underwent either laparoscopic gastric bypass surgery or adjustable gastric banding. Their age, body mass index (BMI), and race were known. Their opening abdominal pressure was recorded by connecting a Verress needle to a pressure monitor. Linear regression was used to assess the contribution of age, race, and BMI to the observed variation in opening abdominal pressure. Neither variation in age or race explained the variation in opening pressure (P > .05). By contrast, variation in BMI explained 8% of the observed variation in opening pressure (P < .05). For every 1 kg/mm(2) increase in BMI, there was on average a 0.07 mm Hg increase in opening pressure. Increases in BMI are associated with increases in intraabdominal pressure.
Related Concept Videos
Intestinal Obstruction II: Pathophysiology
Obesity
Pyloric Obstruction
Increased Intracranial Pressure ll: Pathophysiology
Increased Intracranial Pressure l: Introduction
Appendicitis