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Predictors of self-reported antidepressant adherence.
Tara A Burra1, Edmund Chen, Roger S McIntyre
1Faculty of Medicine, University of Toronto, Ontario, Canada. tara.burra@utoronto.ca
Behavioral Medicine (Washington, D.C.)
|March 14, 2007
Summary
Most patients reported high antidepressant adherence, with practical issues like forgetting being the main reason for nonadherence. Factors influencing nonadherence include side effects, self-efficacy, and education level.
Area of Science:
- Psychiatry
- Psychopharmacology
- Health Psychology
Background:
- Antidepressant adherence is crucial for effective mood disorder management.
- Understanding nonadherence factors is essential for improving treatment outcomes.
Purpose of the Study:
- To assess self-reported antidepressant adherence and reasons for nonadherence.
- To investigate determinants influencing antidepressant nonadherence in mood disorder outpatients.
Main Methods:
- A self-report questionnaire was administered to 80 outpatients with mood disorders.
- The questionnaire assessed beliefs about antidepressants, self-efficacy, and reasons for nonadherence.
Main Results:
- 73% of patients reported taking antidepressants as directed more than 80% of the time.
- Practical issues, such as forgetting medication, were the most common reasons for nonadherence.
- Nonadherence was associated with sexual side effects, lower self-efficacy, being female, and lower educational attainment.
Conclusions:
- While adherence is generally high, practical barriers and specific patient characteristics influence nonadherence.
- Clinicians should address medication efficacy, tolerability, social factors, and health beliefs when prescribing antidepressants.
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