Synergies between intrinsic and synaptic plasticity mechanisms
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Updated: Jul 16, 2026

3D Modeling of Dendritic Spines with Synaptic Plasticity
Published on: May 18, 2020
1Frankfurt Institute for Advanced Studies, Johann Wolfgang Goethe University, 60438 Frankfurt am Main, Germany. triesch@fias.uni-frankfurt.de
Abstract:
We propose a model of intrinsic plasticity for a continuous activation model neuron based on information theory. We then show how intrinsic and synaptic plasticity mechanisms interact and allow the neuron to discover heavy-tailed directions in the input. We also demonstrate that intrinsic plasticity may be an alternative explanation for the sliding threshold postulated in the BCM theory of synaptic plasticity. We present a theoretical analysis of the interaction of intrinsic plasticity with different Hebbian learning rules for the case of clustered inputs. Finally, we perform experiments on the "bars" problem, a popular nonlinear independent component analysis problem.
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