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Updated: Jul 16, 2026

Reprogramming Pancreatic Ductal Adenocarcinoma to Pluripotency
Published on: February 2, 2024
[Pancreatic cancer that was diagnosed two years after palliative treatment]
M A Anía Lahuerta1, J Villalta Cabero
1Servicio de Medicina Interna, Hospital de Barbastro, Huesca. aania@salud.aragon.es
Abstract:
Pancreatic cancer is an aggressive neoplasm, with poor prognosis and survival. As most patients with pancreatic cancer are diagnosed at an advanced stage, the objective of mostly treatment is palliative. Predisposing medical conditions for the development of pancreatic cancer include chronic pancreatitis. The link between the two pathologies is supported in that pancreatic inflammation may play a role in the early development of pancreatic malignancy. The difficulties in discriminating between chronic pancreatitis and adenocarcinoma in the early state, using currently employed diagnosis imaging and tumour marker analysis, result in poor sensitivity and specificity in the diagnosis. We report one case suggestive of pancreatic cancer that was diagnosed two years after palliative treatment.
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Assessment:
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Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
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