Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Multiple palmar keratoacanthomas treated with acitretin.

Gerald A Rosenblum1

  • 1jessashjil@aol.com

Journal of Drugs in Dermatology : JDD
|March 22, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same journal

Pigmented Basal Cell Carcinoma in Skin of Color: A Systematic Review of the Literature.

Journal of drugs in dermatology : JDD·2026
Same journal

Latin America Cutaneous Oncology Management (LACOM) II: A Practical Algorithm for Managing Skin Toxicities in Oncology Patients.

Journal of drugs in dermatology : JDD·2026
Same journal

Efficacy and Tolerability of a Topical Pigment-Correcting Serum in Melasma and Postinflammatory Hyperpigmentation.

Journal of drugs in dermatology : JDD·2026
Same journal

Decoding Sensitive Skin Syndrome: International Expert Advisory Insights on Management From India and the United States of America.

Journal of drugs in dermatology : JDD·2026
Same journal

Evaluating the Safety and Efficacy of Sirolimus Topical Gel 0.2% to Treat Acanthosis Nigricans.

Journal of drugs in dermatology : JDD·2026
Same journal

Moringa-Derived Formulations for Hair Growth, Hair Preservation, and Hair Loss: A Systematic Review.

Journal of drugs in dermatology : JDD·2026

A 62-year-old female with multiple keratoacanthomas achieved complete resolution with a 30-day course of acitretin. Maintenance therapy was required to prevent recurrence of these skin tumors.

Area of Science:

  • Dermatology
  • Oncology

Background:

  • Keratoacanthomas are common skin tumors, often presenting on sun-exposed areas.
  • Surgical or radiation treatments for keratoacanthomas can lead to significant functional impairment, particularly on the hands and wrists.

Observation:

  • A 62-year-old female patient presented with multiple keratoacanthomas affecting the palmar aspects of her hands, wrists, and proximal fingers.
  • The location and multiplicity of the lesions made conventional treatments like surgery or radiation therapy potentially debilitating.

Findings:

  • A 30-day course of oral acitretin at 1 mg/kg per day resulted in complete resolution of the keratoacanthomas.
  • Continuous low-dose maintenance therapy with acitretin (25 mg daily) was necessary to prevent the recurrence of these lesions.

Related Experiment Videos

Implications:

  • Acitretin represents a viable and effective medical treatment option for extensive or functionally sensitive keratoacanthomas.
  • This case highlights the importance of systemic retinoid therapy in managing challenging presentations of keratoacanthoma, offering an alternative to destructive therapies.