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Updated: Jul 16, 2026

A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space
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A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space

Published on: February 1, 2016

Development of a positron-imaging detector with background rejection capability.

Seiichi Yamamoto1, Tatsuya Higashi, Keiichi Matsumoto

  • 1Department of Electrical Engineering, Kobe City College of Technology, 8-3 Gakuen-Higashi-machi, Nishi-ku, Kobe 651-2194, Japan. s-yama@kobe-kosen.ac.jp

Annals of Nuclear Medicine
|March 28, 2007
PubMed
Summary

A new positron-imaging detector enhances intra-operative nuclear medicine. This F-18-fluorodeoxyglucose (FDG)-guided surgery tool offers background rejection for improved surgical accuracy.

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Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor
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A Basic Positron Emission Tomography System Constructed to Locate a Radioactive Source in a Bi-dimensional Space
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Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor
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Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor

Published on: May 7, 2021

Area of Science:

  • Nuclear Medicine
  • Medical Imaging
  • Surgical Instrumentation

Background:

  • Intra-operative probes are crucial in nuclear medicine.
  • F-18-fluorodeoxyglucose (FDG) shows promise for guided surgery.

Purpose of the Study:

  • Develop and test a positron-imaging detector for FDG-guided surgery.
  • Incorporate background rejection capabilities into the detector design.

Main Methods:

  • Utilized a phoswich scintillator array coupled to a multi-channel position-sensitive photomultiplier tube (PSPMT).
  • Employed pulse-shape analysis to differentiate positron events from background gamma events.
  • Integrated plastic scintillators for positron detection and BGO scintillators for annihilation photon detection.

Main Results:

  • Achieved spatial resolution with less than 20% spillover to neighboring pixels.
  • Demonstrated a low background count rate (<2 cps) in phantom studies.
  • The detector system successfully distinguished true positron events from background gamma events.

Conclusions:

  • The developed positron-imaging detector is suitable for FDG-guided surgery.
  • The background rejection capability enhances its utility in nuclear medicine applications.