Related Experiment Video
Updated: Jul 16, 2026

Application of a Dual Upper Limb Task-Oriented Robotic System for the Functional Recovery of the Upper Limb in Stroke Patients
Published on: October 11, 2024
Improving hand function in stroke survivors: a pilot study of contralaterally controlled functional electric
Jayme S Knutson1, Mary Y Harley, Terri Z Hisel
1Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA. jsk12@case.edu
Objective:
To assess the feasibility of a new stroke rehabilitation therapy for the hemiparetic hand.
Design:
Case series. Pre- and postintervention assessment with 1- and 3-month follow-ups.
Setting:
Clinical research laboratory of a large public hospital.
Participants:
Three subjects with chronic (>6mo postcerebrovascular accident) upper-extremity hemiplegia.
Intervention:
Subjects used an electric stimulator to cause the paretic hand extensor muscles to contract and thereby open the hand. Subjects controlled the intensity of the stimulation, and thus the degree of hand opening, by volitionally opening the unimpaired contralateral hand, which was detected by an instrumented glove. For 6 weeks, subjects used the stimulator to perform active repetitive hand-opening exercises 2 hours daily at home and functional tasks 1.5 hours twice a week in the laboratory.
Main Outcome Measures:
Maximum voluntary finger extension, maximum voluntary isometric finger-extension moment, finger-movement control, and box and block test (BBT) score at pre- and posttreatment and at 1 month and 3 months posttreatment.
Results:
Maximum voluntary finger extension increased from baseline to end of treatment and from the end of treatment to 1-month follow-up in 2 subjects. Maximum voluntary isometric finger-extension moment, finger-movement control, and BBT score increased from baseline to the end of treatment and from the end of treatment to 1-month follow-up in all 3 subjects. The improvements generally declined at 3 months.
Conclusions:
The results suggest a positive effect on motor impairment, meriting further investigation of the intervention.

