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Photochemical determination of different DNA structures.

Yan Xu1, Ryu Tashiro, Hiroshi Sugiyama

  • 1Department of Chemistry, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606-8502, Japan.

Nature Protocols
|April 3, 2007
PubMed
Summary

This study introduces a photochemical method using 5-halouracil to detect various DNA structures, including A, B, Z forms, kinks, and G-quadruplexes. The technique analyzes photoproducts to reveal detailed relationships between DNA conformation and photochemical reactions.

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