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Cutaneous malignant ossifying fibromyxoid tumor
Thomas L Cibull1, Steven D Billings
1Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana 46202-5126, USA.
The American Journal of Dermatopathology
|April 7, 2007
Summary
A rare malignant ossifying fibromyxoid tumor (OFMT) presented as a buttock mass. Despite aggressive histologic features, the patient recovered after surgery, showing no signs of recurrence.
Area of Science:
- Oncology
- Pathology
- Surgical Oncology
Background:
- Ossifying fibromyxoid tumor (OFMT) is a rare neoplasm.
- While typically found in deep soft tissues, OFMT can rarely manifest as a cutaneous tumor.
Observation:
- A 76-year-old woman presented with a 3 cm buttock mass.
- Histologic examination revealed a highly cellular tumor with significant nuclear atypia, necrosis, and a high mitotic rate (17 MF/50 HPF).
- The tumor displayed features suggestive of malignancy, including a lobular arrangement and bone formation.
Findings:
- The buttock mass was diagnosed as a malignant ossifying fibromyxoid tumor (OFMT).
- Malignant OFMT, characterized by high nuclear grade, cellularity, and mitotic rate, carries a risk of aggressive behavior and metastasis.
- The patient underwent wide excision for the malignant OFMT.
Implications:
- This case highlights the potential for OFMT to present as a cutaneous malignancy.
- Aggressive histologic features in OFMT warrant classification as sarcoma and consideration of adjuvant therapy.
- Early detection and surgical management are crucial for improving outcomes in malignant OFMT.
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