Related Experiment Video
Updated: Jul 15, 2026
07:48
Intravenous Endotoxin Challenge in Healthy Humans: An Experimental Platform to Investigate and Modulate Systemic Inflammation
Published on: May 16, 2016
Effect of endotoxemia on skin antioxidant enzymes under experimental conditions
A V Ivanova1, E V Mikhal'chik, E A Miroshnikova
1Russian State Medical University; Russian People's Friendship University, Moscow.
Bulletin of Experimental Biology and Medicine
|April 7, 2007
Abstract:
Intraperitoneal injection of bacterial lipopolysaccharide in a dose of 1 mg/kg was followed by prestimulation of whole blood leukocytes in rats. Activities of peroxide- and lipoperoxide-utilizing antioxidant enzymes glutathione peroxidase, glutathione S-transferase, and catalase increased 1 day after lipopolysaccharide administration, while the content of malonic dialdehyde in the skin remained unchanged.
