Related Experiment Video
Updated: Jul 15, 2026

Isolating Nasal Olfactory Stem Cells from Rodents or Humans
Published on: August 22, 2011
Multipotent stem and progenitor cells of the olfactory epithelium
I V Viktorov1, E A Savchenko, O V Ukhova
1V. P. Serbsky State Research Center of Social and Forensic Psychiatry, Moscow. victorov_iv@bk.ru
Abstract:
In recent decades, a wide spectrum of fetal and embryonic stem and progenitor cells were used for cell therapy of diseases of the central nervous system, but the olfactory glial ensheathing cells exhibited certain advantages due to their biological properties and capacity to stimulate regeneratory processes in spinal injury. The therapeutic effect of a heterogeneous complex of olfactory epithelial cells is more pronounced; apart from glial ensheathing cells, this complex includes fibroblasts, Schwann cells, stem and progenitor cells of this structure. The use of minimally invasive methods for isolation of human olfactory epithelial tissue is important for clinical practice, because they provide cells for autologous transplantation and rule out graft rejection immune reaction and the risk of transmission viral infection and transfer of genetic defects, which can be associated with allotransplantation.
Related Concept Videos
Olfactory Receptors: Location and Structure
Olfaction
The olfactory receptors are embedded in the cilia of the...
Physiology of Smell and Olfactory Pathway
The olfactory...
Source And Potency Of Stem Cells
Multipotency and Niche of Bulge Stem Cell
Adult Stem Cells
