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A Stable Phantom Material for Optical and Acoustic Imaging
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Published on: June 16, 2023

Noninvasive fluid property measurements using acoustic methods.

Michael Forbush1, Humphrey Chow, James Chiao

  • 1EDC BioSystems, 1804 McCarthy Boulevard, Milpitas, CA 95035, USA. mforbush@edcbiosystems.com <mforbush@edcbiosystems.com>

Clinics in Laboratory Medicine
|April 10, 2007
PubMed
Summary

This study introduces a noninvasive acoustic wave technique to measure fluid properties. This method accurately determines the concentration of solutions like DMSO and water without sample contamination.

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Area of Science:

  • Physical Chemistry
  • Acoustics
  • Fluid Dynamics

Background:

  • Traditional fluid property measurements are often invasive, risking sample contamination or consumption.
  • Noninvasive techniques are crucial for analyzing small or valuable fluid samples.
  • Fluid properties, like surface tension, can infer other characteristics, such as concentration.

Purpose of the Study:

  • To develop and validate a noninvasive method for determining fluid properties.
  • To utilize acoustic wave excitation and monitoring for fluid analysis.
  • To establish a technique for precise concentration determination in solutions.

Main Methods:

  • Employing acoustic waves to excite and simultaneously monitor the surface of a liquid.
  • Measuring the fluid's response to acoustic excitation.
  • Correlating the measured response to fluid properties and concentration.

Main Results:

  • Successfully determined the concentration of dimethyl sulfoxide (DMSO) and water solutions.
  • Demonstrated the feasibility of using acoustic surface wave analysis for concentration measurement.
  • Validated the noninvasive nature of the technique, preserving sample integrity.

Conclusions:

  • Acoustic wave-based surface analysis offers a noninvasive alternative for fluid property determination.
  • This method enables accurate concentration measurements, crucial for precise solution preparation.
  • The technique is valuable for applications involving limited or sensitive fluid samples.