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A fully automated robotic system for high throughput fermentation.

Hartmut F Zimmermann¹, Jochen Rieth

¹Degussa AG, Creavis Technologies & Innovation, Hanau, Wolfgang, Germany. hartmut.zimmermann@degussa.com <hartmut.zimmermann@degussa.com>

Clinics in Laboratory Medicine

|April 10, 2007

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High throughput robotic systems automate biochemical assays. A new automated solution addresses key industrial fermentation demands like oxygen supply and contamination control for improved process development.

Area of Science:

Biotechnology
Biochemical Engineering
Process Automation

Background:

High throughput robotic systems have been utilized for biochemical assays since the 1990s.
Industrial fermentation process development presents unique challenges not fully addressed by existing systems.

Purpose of the Study:

To present a fully automated solution for industrial fermentation process development.
To address critical demands including oxygen supply, temperature control, evaporation minimization, contamination avoidance, and process monitoring.

Main Methods:

Development of a fully automated robotic system.
Integration of specific modules to manage oxygen supply, temperature, and evaporation.
Implementation of contamination control measures.

Related Experiment Videos

Incorporation of simple and reliable process monitoring tools.

Main Results:

The presented automated solution effectively manages critical parameters for industrial fermentation.
Demonstrated successful integration of oxygen supply, temperature control, and evaporation minimization.
Achieved reliable process monitoring and contamination avoidance.

Conclusions:

The developed automated system meets the specific demands of industrial fermentation process development.
This solution offers a robust platform for optimizing fermentation processes.
Automation is key to advancing efficient and reliable industrial fermentation.