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Updated: Jul 15, 2026

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Athymic Rat Model for Evaluation of Engineered Anterior Cruciate Ligament Grafts
Published on: March 26, 2015
Anterior cruciate ligament reconstruction using compressed bone-hamstring-bone graft.
Miroslav Milankov1, Natasa Miljkovic, Drgan Savic
1Department of Orthopaedic Surgery and Traumatology, Institute of Surgery, Clinical Center, Medical School, University of Novi Sad, Novi Sad, State Union of Serbia and Montenegro. milankom@eunet.yu
Summary
The modified bone-hamstring-bone (BHB) graft offers strong initial fixation for faster rehabilitation. This technique enhances graft security and promotes biological healing without causing patellofemoral issues.
Area of Science:
- Orthopedic Surgery
- Sports Medicine
- Biomedical Engineering
Background:
- Graft fixation is critical for early rehabilitation in anterior cruciate ligament (ACL) reconstruction.
- Existing bone-patellar tendon-bone and hamstring tendon grafts have limitations.
- A hybrid approach may overcome these disadvantages.
Purpose of the Study:
- To describe a modified bone-hamstring-bone (BHB) composite graft procedure.
- To highlight the technique's advantages for graft fixation and patient outcomes.
Main Methods:
- A modified BHB composite graft technique is detailed.
- Cancellous bone cylinders are harvested and secured to the hamstring graft ends with sutures.
- Graft ends are pressed to achieve a diameter of 9-10 mm for strong fixation.
- Graft is inserted into tibial and femoral tunnels and secured with round cannulated interference screws (RCI).
Main Results:
- The modified BHB technique provides precise and strong initial graft fixation.
- This method promotes biological fixation, aiding graft incorporation.
- The procedure avoids patellofemoral joint complications.
Conclusions:
- The modified BHB graft technique ensures robust early fixation, crucial for rehabilitation.
- This hybrid graft method offers advantages over traditional techniques.
- The procedure is associated with favorable outcomes and no patellofemoral issues.
